In this study, the hypothesis that the 12-week Tai Chi Quan training would have better control of blood sugar, biochemistry profile, and also better quality of life and activity of autonomic nerve system (ANS). The subjects were randomize assigned to either Tai Chi group or control group. The outcome measures before and after 12-week intervention include basic demographic characteristics, HbA1c, fasting blood glucose(FBG), triglycerides (TG), high and low density lipoprotein (HDL, LDL), creatinine(Cr), eGFR, GPT, ACR, quality of life, and activity of automatic nerve system.
In this study, the hypothesis that the 12-week Tai Chi Quan training would have better control of blood sugar, biochemistry index, and also better quality of life and activity of automatic nerve system. In the study, type 2 diabetes mellitus(T2DM) patients will be recruited as subjects. The subjects were randomized to either Tai Chi group or control group. Tai Chi group would take Tai Chi Quan training for 1hr, twice a week for 12 weeks. There were 10-minute warm-up, 40-minute Tai Chi lesson, and 10-minute cool-down exercise in the training. In this study, the 1st section of Yang style 108 form is chosen for the experiment group. Both group were given diabetic patients care education and the exercise recording book for encouraging the daily exercise habits. The outcome measures before and after 12-week intervention include basic demographic characteristics, HbA1c, fasting blood glucose, triglycerides, high and low density lipid, creatinine, eGFR, GPT, ACR, quality of life, and activity of automatic nerve system.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
60
the first section of Yang style 108 form, including 10-minute warm-up, 40-minute training, and 10-minute cool-down exercise, twice a week
Linsen Chinese Medicine and Kunming Branch, Taipei City Hospital
Taipei, Taiwan
RECRUITINGHemoglobin
HbA1c
Time frame: change from Baseline to 12 weeks
fasting blood glucose
blood sample after 8-hour fasting
Time frame: change from Baseline to 12 weeks
triglycerides
blood sample after 8-hour fasting
Time frame: change from Baseline to 12 weeks
high and low density lipoprotein
blood sample after 8-hour fasting
Time frame: change from Baseline to 12 weeks
creatinine
blood sample after 8-hour fasting
Time frame: change from Baseline to 12 weeks
estimated Glomerular Filtration Rate (eGFR)
blood sample after 8-hour fasting
Time frame: change from Baseline to 12 weeks
Glutamic-Pyruvic Transaminase (GPT)
blood sample after 8-hour fasting
Time frame: change from Baseline to 12 weeks
urine albumin/creatinine ratio (ACR)
from urine sample
Time frame: change from Baseline to 12 weeks
quality of life
WHOQOL-BREF Taiwan
Time frame: change from Baseline to 12 weeks
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heart rate variability
represent for balance of autonomic nervous system
Time frame: change from Baseline to 12 weeks
low frequency (LF)
Low frequency is the frequency domain analysis from heart rate variability, and is represent for sympathetic nervous system
Time frame: change from Baseline to 12 weeks
high frequency (HF)
High frequency is the frequency domain analysis from heart rate variability, and is represent for parasympathetic nervous system
Time frame: change from Baseline to 12 weeks