MRI 3D UTE Hyper-Cones & ZTE for PET/MR Lung Attenuation Correction & for Lung Diagnostic Imaging

University of Zurich9 enrolled

Overview

MRI 3D UTE Hyper-Cones \& ZTE for PET/MR lung attenuation correction \& for lung diagnostic imaging

The primary objective is to clinically test the feasibility of 3D UTE Hyper-Cones \& ZTE in capturing lung density of patients with lung diseases at reasonable clinical imaging times compared to standard MR lung protocols (LAVA-Flex, PROPELLER). Secondly, we want to investigate if Hyper-Cones \& ZTE can be used for lung imaging such as vessels and air-pathways, oncological patients, lung nodules and lung infiltration \& parenchyma pathophysiology such as chronic obstructive pulmonary disease.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Lung Diseases

Interventions

PET/MR image acquisitionDIAGNOSTIC_TEST

Acquisition of PET and MR sequences on SIGNA PET/MR device.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * informed consent and signature * clinical PET/CT planned and performed at Wagi site in Schlieren * male or female patients * from 18 to 80 years of age. Exclusion Criteria: \- same exclusion criteria as for the clinical PET/CT exam (i.e. pregnant women). Additional exclusion criteria: \- standard exclusion criteria for clinical MRI (evaluated by clinical standard determined by MRI questionnaire).

Locations (1)

University Hospital Zurich, Department of Nuclear Medicine

Zurich, Switzerland

Outcomes

Primary Outcomes

Confirm that lung density map extraction is feasible through Hyper-Cones & ZTE scanning.

Confirm that lung density map extraction is feasible through Hyper-Cones \& ZTE scanning.

Time frame: 1 year

Data from ClinicalTrials.gov

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