The study is a prospective, randomized, controlled, exploratory trail to evaluate the strategy of "one-stop" endovascular treatment for concomitant coronary artery disease and aortic atherosclerotic disease.
60 patients will be allocated randomly in a 1:1 ratio into one-stop strategy group or staging strategy group. In one-stop strategy group, percutaneous coronary intervention (PCI) will be performed on the same operating room immediately after the endovascular aortic repair (EVAR); In staging strategy group, PCI will be performed several days after EVAR. The safety and effectiveness will be assessed between two groups 1 year after the operation. The economic index will be evaluated as well as.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Percutaneous coronary intervention (PCI) will be performed on the same operating table immediately after the endovascular aortic repair (EVAR)
Chinese Academy of Medical Sciences, Fuwai Hospital
Beijing, Beijing Municipality, China
Perioperative major bleeding (BARC≥3 grade)
Time frame: 12 months
Difference of operative success rate between two groups
Time frame: 12 months
Difference of incidence of all-cause death between two groups
Time frame: 12 months
Difference of incidence of myocardial infarction between two groups
Time frame: 12 months
Difference of incidence of rupture of aorta between two groups
Time frame: 12 months
Difference of incidence of bleeding events (BARC 2 grade) between two groups
Time frame: 12 months
Difference of incidence of pseudoaneurysm between two groups
Time frame: 12 months
Difference of incidence of Stent thrombosis between two groups
Time frame: 12 months
Composite of average in-patient time and average cost during hospitalization
Time frame: 12 months
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