The purpose of the study is to determine to what extent the abdominal muscles contribute to airway pressure, in order to investigate the correlation between muscles weakness and extubation outcome in mechanically ventilated patients. In addition the reliability of the sonographic measurements will be assessed.
The purpose of the study is to determine to what extent the abdominal muscles contribute to airway pressure, in order to investigate the correlation between muscles weakness and extubation outcome in mechanically ventilated patients. In addition the reliability of the sonographic measurements will be assessed.
Study Type
OBSERVATIONAL
Enrollment
35
Abdominal muscles ultrasound during a spontaneous breathing trial using the M-mode to calculate the thickening fraction of the anterior and lateral abdominal muscles under multiple circumstances (tasks performed by the patients)
Toronto General Hospital Research Institute
Toronto, Canada
Spedali Civili di Brescia
Brescia, Italy
Correlation between thickening fraction and SBT outcome
Correlation between thickening fraction of each muscles evaluated by ultrasound before the SBT and the SBT outcome.
Time frame: Measurements will be performed before SBT
Correlation between the pressures generated by respiratory muscles and SBT outcome
Correlation between the pressures generated by respiratory muscles during the ultrasound measurements (Twice Transdiaphragmatic pressure, TwPdi; maximal inspiratory pressure, MIP) and SBT outcome
Time frame: Measurements will be performed before SBT
Inter-rater agreement
Concordance of measurements of abdominal muscle thickness and thickening fraction in mechanically ventilated patients performed by two different observers will be evaluated.
Time frame: Measurements will be performed before SBT
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