Patients with kidney cancer often undergo hand-assisted laparoscopic nephrectomy or Robot assisted partiel nephrectomy. The investigators performed a one-year retrospective study. the sudy revealed that 67% of the patients needed substantial amounts of opioids for postoperative pain management (PPM) in recovery despite a multimodal analgesic regime. In a prospective pilot study including ten laparoscopic hand-assisted nephrectomy, with severe postoperative pain the investigators found that bilateral Ultrasound-guided (USG) transmuscular quadratus lumborum (TQL) block substantially reduced pain and opioid consumption. This study aims to evaluate the effect on PPM of a bilateral USG TQL block compared to placebo.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
50
Single shot of ropivacaine 0.325%
Single shot of saline 0.9%
Zealand university Hospital, Anaesthesiology
Roskilde, Denmark
opioid consumption
Opioid consumption postoperatively: data from Patient Controlled Analgesia(PCA) pump and patient medical record).
Time frame: 12 hours postoperatively
opioid consumption
Opioid consumption postoperatively (data from PCA pump and patient medical record).
Time frame: 6 hours postoperatively
opioid consumption
Opioid consumption postoperatively (data from PCA pump and patient medical record).
Time frame: 18 hours postoperatively
opioid consumption
Opioid consumption postoperatively (data from PCA pump and patient medical record).
Time frame: 24 hours postoperatively
NRS score
Numeric Rating Scale(NRS). Scores range from 0-10, 0=no pain-10=worst pain postoperatively at rest and activity
Time frame: 12 hours postoperatively
NRS score at rest and activity
Numeric Rating Scale(NRS). Scores range from 0-10, 0=no pain-10=worst pain
Time frame: 6 hours postoperatively
NRS score at rest and activity
Numeric Rating Scale(NRS). Scores range from 0-10, 0=no pain-10=worst pain
Time frame: 18 hours postoperatively
NRS score at rest and activity
Numeric Rating Scale(NRS). Scores range from 0-10, 0=no pain-10=worst pain
Time frame: 24 hours postoperatively
Opioid-related side effects
The degree of morphine-related side effects (PONV, itching, fatigue, etc.)
Time frame: 6 hours postoperatively
Opioid-related side effects
The degree of morphine-related side effects (PONV, itching, fatigue, etc.)
Time frame: 12 hours postoperatively
Opioid-related side effects
The degree of morphine-related side effects (PONV, itching, fatigue, etc.)
Time frame: 18 hours postoperatively
Opioid-related side effects
The degree of morphine-related side effects (PONV, itching, fatigue, etc.)
Time frame: 24 hours postoperatively
Patient satisfaction with application of the block. NRS
Numeric Rating Scale(NRS). Scores range from 0-10, 0=no pain-10=worst pain
Time frame: Immediately after application of the block
Ambulation
Time from operation to ambulation
Time frame: within 24 hours postoperatively
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