Comparison of Different Fluence Settings for Yellow Subthreshold Laser Treatment in Diabetic Macular Edema

L.V. Prasad Eye Institute32 enrolled

Overview

To assess the safety and efficacy of two subthreshold parameters (5% and 15% duty cycle (DC)) compared to standard ETDRS (early treatment of diabetic retinopathy study) continuous wave (CW) laser

Test burn up to barely visible burn with micropulse laser, then reduce the power by 70% and perform laser with various DC (5%, 15%, cw) as per the group. Focal to Mas+ confluent burns to areas of diffuse leakage

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diabetic Retinopathy

Interventions

LaserPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Eyes with DME (center or non-center involving) with \<350 microns central retinal thickness Exclusion Criteria: * Subfoveal exudates, history of VR surgery, history of macular laser

Outcomes

Primary Outcomes

1. Decrease in number of leaking Mas on FFA 2. Decrease in diffuse leakage on FFA

Comparing the number of leaking microaneuyrms baseline to 6 weeks with 3 types of lasers (two subthreshold parameters (5% and 15% duty cycle (DC)) compared to standard ETDRS continuous wave (CW) laser.

Time frame: 3 months

Data from ClinicalTrials.gov

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