The aim of the study is to determine if time-restricted feeding (TRF) is an effective dietary strategy to weight loss after 8 weeks intervention. TRF will be compared with an intervention without restriction in time for feeding. Both strategies will be with caloric restriction.
The participants of the study will be divided in two groups: (1) a group with caloric restriction and without restriction in time for feeding and (2) a group with caloric restriction and restriction in time for feeding. This second group will be subdivided according to the participant's preference: (2.1) first meal at 8 a.m. and last meal at 4 p.m. or (2.2) first meal at 12 p.m. and last meal at 8 p.m. The caloric restriction for all participants will be 513 to 770 kcal from estimated energy requirement.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
45
Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements), without restriction in time for feeding, for 8 weeks.
Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 12 p.m. to 8 p.m.) and 16 hours of fasting, for 8 weeks.
Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 8 a.m. to 4 p.m.) and 16 hours of fasting, for 8 weeks.
Hospital da Clínicas
Belo Horizonte, Minas Gerais, Brazil
RECRUITINGHospital das Clínicas
Belo Horizonte, Minas Gerais, Brazil
RECRUITINGChange in body weight
Body weight will be assessed by mechanical scale
Time frame: Baseline and weeks 2, 4 and 8
Change in body composition
Body composition will be assessed by electrical bioimpedance
Time frame: Baseline and weeks 2, 4 and 8
Change in resting energy expenditure
Resting energy expenditure will be assessed by indirect calorimetry
Time frame: Baseline and weeks 2, 4 and 8
Change in self-reported energy intake
Dietary energy intake will be assessed with 3-days food records
Time frame: Baseline and weeks 2, 4 and 8
Change in self-reported diet composition
Dietary macronutrient intake will be assessed with 3-days food records
Time frame: Baseline and weeks 2, 4 and 8
Change in self-reported intervention adherence
Adherence will be assessed by daily record of feeding hours
Time frame: Baseline and weeks 2, 4 and 8
Change in metabolic profile
Fasting lipids, glucose and free fatty acids
Time frame: Baseline and weeks 2, 4 and 8
Change in self-reported stress
Self-reported stress will be assessed by a questionnaire (Perceived Stress Scale). The total of the scale is a sum of scores of 14 questions. Total score can range from zero to 56. The higher the score, the higher the level of stress.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Baseline and weeks 2, 4 and 8
Change in self-reported anxiety
Self-reported anxiety will be assessed by a questionnaire (Beck Anxiety Inventory). The questionnaire consists of 21 items and the severity of each of them scored from 0 to 3. The degree of anxiety will be classified according to the final score obtained: 0-7 absent or minimum; 8-15 light; 16-25 moderate; 26-63 severe.
Time frame: Baseline and weeks 2, 4 and 8
Change in self-reported depression
Self-reported depression will be assessed by a questionnaire (Beck Depression Inventory). The questionnaire consists of 21 items and the severity of each one scored from 0 to 3. The volunteers will be classified according to the score obtained: BDI ≤ 15: without depression; 16 ≤ BDI ≤ 20: dysphoria; BDI\> 20: depression.
Time frame: Baseline and weeks 2, 4 and 8