A Study to Determine the Epidemiology and Evaluate the Burden of Disease in Respiratory Syncytial Virus/Human Metapneumovirus and Influenza A Infected Hospitalized Participants (Adults and Children)

Number of Participants (Adults) with RSV, Influenza A and hMPV Infections

Number of Adult participants with RSV, Influenza A and hMPV Infections will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Number of Participants (infants/children) with RSV and hMPV Infection

Number of infants/children participants with RSV and hMPV infection will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Number of Participants in Various Subgroups of Hospitalized Patients by Type of Respiratory Pathogen

Number of participants in various subgroups (eg, comorbidities, premature infants, elderly, immunocompromised) of Hospitalized Patients by Type of Respiratory Pathogen (RSV, influenza A, and hMPV in adults and RSV and hMPV in infants/children less then or equal to (\<=) 5 years of age) will be characterized.

Time frame: During hospitalization (up to maximum 12 months)

Symptoms of Participants Presenting at Hospital

Symptoms of Participants Presenting at Hospital (outpatient clinic, emergency room/emergency department \[ER/ED\], or general ward) and at discharge will be assessed.

Time frame: At admission (Day 1) and at discharge

Number of Participants Without Presenting Symptoms of Acute Respiratory Tract Infection (ARTI)

Number of participants without presenting symptoms among participants with PCR-confirmed RSV, influenza A, or hMPV infections of ARTI will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Number of Participants with Respiratory Infections of Nosocomial Origin With or Without Presenting Symptoms

Number of participants with respiratory infections of nosocomial origin with or without presenting symptoms among participants with PCR-confirmed RSV, influenza A, or hMPV infections will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Patient Journey

The number of patients admitted to different hospital-locations (ED/ER department, Ward, Outpatient clinic, ICU, Other), their provenances, the number of patients being transferred to ICU and the number of patients being thereafter re-hospitalized will be assessed.

Time frame: During hospitalization and up to 6 months after discharge

Criteria Applied for the Index-Hospitalization, Transfer to ICU, Discharge From Hospital

The distribution of the primary reasons for the index-hospitalization, the distribution of the primary reasons for ICU transfer, the distribution of the criteria used to discharge from the index-hospitalization (including hospital recovery scale (HRS) and oxygen saturation) will be assessed.

Time frame: At admission, at ICU admission, at discharge (up to maximum 12 months)

Participant's Clinical Status Assessed by Hospital Recovery Scale (HRS)

The hospital recovery scale assesses a participant's clinical status. The scale provides 6 mutually exclusive conditions ordered from best to worst: 1) not hospitalized; 2) non-ICU hospitalization, not requiring supplemental oxygen; 3) non-ICU hospitalization, requiring supplemental oxygen; 4) admitted to the ICU, not requiring invasive mechanical ventilation; 5) requiring invasive mechanical ventilation; and 6) death.

Time frame: Baseline, Day 4, Day 6 and Day 14

Change of National Early Warning Score (NEWS) for Adults at Admission, Day 3, and Day 6

The NEWS provides guidance for 3 scores: Low score (1-4) should prompt assessment by a competent registered nurse who should decide if a change to frequency of clinical monitoring or an escalation of clinical care is required; Medium score (5-6) should prompt an urgent review by a clinician skilled with competencies in the assessment of acute illness; and High score (7 or more) should prompt emergency assessment by a clinical team/critical care outreach team with critical-care competencies.

Time frame: At admission (Day 1), Day 3, and Day 6

CRB-65 Scoring System at Admission to the Hospital for Adults with Lung Disease and the Relevance on Medical Resource Utilization (MRU) by type of Respiratory Pathogen

Confusion, respiratory rate greater than or equal to (\>=) 30/minute, low systolic less than (\<) 90 millimeter of mercury (mm Hg) or diastolic less than or equal to (=\<) 60 mm Hg blood pressure, age \>= 65 years (CRB-65) scoring system at admission to the hospital for adults with lung disease and the relevance on MRU by type of Respiratory Pathogen will be assessed. CRB-65 Scale ranges from 0 to 4. Score 0 = Very low risk of death, Score 1 and 2 = Increased risk of death and 3 or 4 = High risk of death.

Time frame: At admission (Day 1)

Acute Physiologic and Chronic Health Evaluation (APACHE II) Scores in Adults at ICU Admission and the Relevance on MRU by Type of Respiratory Pathogen

The APACHE II is a validated severity of disease classification system. It uses a point score based on initial values of 12 routine physiologic measurements (temperature, mean arterial pressure, heart rate, respiratory rate, oxygenation, arterial pH, serum sodium, potassium, and creatinine, hematocrit, white blood cell count, Glasgow coma score), age, and previous health status to provide a general measure of severity of disease. An increasing score (range 0 to 71) is closely correlated with subsequent risk of hospital death for intensive care admissions.

Time frame: At ICU admission (up to maximum 12 months)

Simplified Acute Physiology Scores 3 (SAPS 3) in Adults at ICU Admission and the Relevance on MRU by Type of Respiratory Pathogen

The SAPS 3 consists of 20 variables: age, co-morbidities, use of vasoactive drugs before ICU admission, intrahospital location before ICU admission, and length of stay in the hospital before ICU admission, reason(s) for ICU admission, planned/unplanned ICU admission, surgical status at ICU admission, anatomic site of surgery, and presence of infection at ICU admission and place acquired, lowest estimated Glasgow coma scale, highest heart rate, lowest systolic blood pressure, highest bilirubin, highest body temperature, highest creatinine, highest leukocytes, lowest platelets, lowest hydrogen ion concentration (pH), and ventilatory support and oxygenation. Score varies from a minimum of 0 points to a maximum of 217 points. Higher scores indicate higher severity.

Time frame: At ICU admission (up to maximum 12 months)

Medical Resources Utilization by Type of Virus Infection

MRU in adults by type of virus infection (RSV A, RSV B, influenza A, influenza B, hMPV, any other virus infection if available) at baseline that is before hospitalization will be collected.

Time frame: Baseline

Medical Resources Utilization by Estimated Glomerular Filtration Rate (eGFR)

MRU in adults by eGFR at baseline that is before hospitalization will be collected. The glomerular filtration rate is an indicator of renal function and is calculated based on serum creatinine.

Time frame: Baseline

ReSVinet score used at Time of Admission to the Hospital in Infants/Children, and Relevance on MRU by Type of Respiratory Pathogen

ReSVinet scale is based on seven parameters (feeding intolerance, medical intervention, respiratory difficulty, respiratory frequency, apnoea, general condition, fever) which are assigned different values (from 0 to 3) for a total of 20 points. Higher scores indicate higher severity.

Time frame: At Admission (Day 1)

Levels of White Blood cell During Hospitalization

Levels of White Blood cell Count during hospitalization will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Levels of Neutrophils During Hospitalization

Levels of Neutrophils during hospitalization will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Levels of Procalcitonin During Hospitalization

Levels of Procalcitonin during hospitalization will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Levels of C-Reactive Protein During Hospitalization

Levels of C-Reactive Protein during hospitalization will be reported.

Time frame: During hospitalization (up to maximum 12 months)

Levels of Viral Load During Hospitalization

Levels of Viral Load during hospitalization will be reported.

Time frame: During hospitalization (up to maximum 12 months)