Combine TACE and Autologous Tcm Immunotherapy Versus TACE Alone for HCC With MVI After Radical Resection

Inclusion Criteria: 1. Be willing and able to provide written informed consent for the study. 2. Subject has accepted radical hepatic resection, and preoperative imaging is no vascular invasion. 3. Postoperative pathology confirmed Hepatocellular carcinoma with negative margin and microvascular invasion (MVI). 4. Age between 18-75 years old. 5. Radiology confirmed complete response (CR) after radical surgery. 6. Child-Pugh A. 7. Eastern Cooperative Oncology Group(ECOG) body condition score 0. 8. Adequate hepatic and renal function: Hemoglobin ≥ 9.0g/dl. Absolute neutrophil count (ANC) \> 1,500/mm3. Platelets ≥ 50,000/ul. Total bilirubin (TBIL) ≤ 2mg/dl. Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) ≤ 5 the upper limit of normal (ULN) for the institution. Alkaline phosphatase (ALP) ≤ 4 the upper limit of ULN. Prothrombin time (PT) \> 50% or prothrombin time-international normalized ratio (PT-INR) \< 2.3. Serum creatinine (CREA) ≤ 1.5 the upper limit of ULN. 9. Female subjects have had a negative blood pregnancy test within 2 week, 10. Subjects be willing to use appropriate contraception during the trial and 2 weeks after the last administration of immunotherapy. 11. Radiology such as CT and MRI were performed in 4 weeks before the study. Exclusion Criteria: 1. Recurrent HCC. 2. Portal vein embolus. 3. Cardiovascular disease: Evidence of NYHA functional class III or IV heart disease. Unstable coronary artery disease (CAD) is not allowed, while Myocardial Infarction (MI) 6 months of starting study is allowed. Cardiac arrhythmias requiring antiarrhythmic drugs except β-blockers or digoxin are not allowed. Uncontrolled hypertension. 4. History of Human Immunodeficiency Virus (HIV) or syphilis infection. 5. Severe inflammation, NCI CTCAE Version 3.0 grade \> 2. 6. Epilepsy requiring steroid or antiepileptic drugs. 7. History of allotransplantation. 8. History or any evidence of hemorrhage. 9. Subjects undergoing renal dialysis. 10. Pregnancy or breast-feeding. 11. Prior or undergoing cancers that primary sites are different from the carcinoma of this study. Exceptions to this are: Cervical carcinoma in situ (CIS) Cured basal cell carcinoma Superficial bladder tumor Cured cancers over 3 years before the study 12. Uncontrolled Ascites by diuretic treatment. 13. History of encephalopathy. 14. Gastrointestinal hemorrhage in 30 days before the study. 15. History of esophageal variceal hemorrhage and it is no effective treatment to prevent the recurrence of hemorrhage. 16. Major surgery except radical hepatic resection was performed in 4 weeks before the study. 17. Autologous bone marrow transplantation (ABMT) in 4 weeks before the study. 18. Concurrent treatment on another clinical trial or treatment on another clinical trial in 4 weeks before the study. 19. Drug abuse, medical treatment, mental illness or social disorders that would interfere with subjects' participation, or confound the results of the trial. 20. Any condition that would interfere with or endanger the safety and compliance of subjects.