Hyperbaric Oxygen Therapy in Children With Inflammatory Bowel Diseases

Inclusion Criteria: * diagnosis of Crohn's disease or ulcerative colitis according to the criteria from Porto - based on the clinical condition as well as imaging and endoscopic examinations with histopathological assessment; * failure to achieve the remission despite the use of standard treatment in accordance with international guidelines; * written consent of the patient's legal guardians and the patient himself if he/she turns 16 years of age. Exclusion Criteria: * intolerance of enclosed spaces; * contraindications for hyperbaric therapy: otolaryngological (otitis media, sinusitis); cardiac (clinically significant defects or arrhythmias); pneumological (clinically significant defects) * exacerbation of inflammatory bowel disease during the therapy; * contraindications for hyperbaric therapy in a patient's caregiver in a situation, where the patient requires his/hers presence inside the hyperbaric chamber during the session.