The Gut and Skin Microbiome in Vitiligo Disease Progression

Northwestern University100 enrolled

Overview

Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls. The investigators aim to answer the question whether the gut and skin microbiome of patients with vitiligo differs from the general population.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Vitiligo Healthy

Eligibility

Sex: ALLMin age: 18 YearsMax age: 89 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with and/or without vitiligo lesional expansion over the past year. * Age/sex-matched controls who do not have a diagnosis of vitiligo * Subjects who are age 18-89 years of age at time of enrollment * Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443) Exclusion Criteria: * Subjects who are younger than 18 years of age or 90 years of age or older * Subjects who are unable to give consent

Locations (1)

Northwestern University

Chicago, Illinois, United States

RECRUITING

Outcomes

Primary Outcomes

Microbiome composition

Diversity analysis of microbiome samples in control subjects versus vitiligo subjects (measured by number of bacteria species/sample)

Time frame: 12 months

Disease Progression

Disease progression in control subjects versus vitiligo subjects (measured by VASI score (0-100)).

Time frame: 12 months

Secondary Outcomes

Diet History Food Frequencies

Scoring from diet history food frequency questionnaires (measured by average daily food frequency scores).

Time frame: 12 months

Central Contacts

Dermatology CTU

CONTACT

312-503-5944 NUdermatologyCTU@northwestern.edu

Data from ClinicalTrials.gov

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