Acute severe ulcerative colitis \[ASUC\] patients have high risk of no response to medical treatments and might miss the best timing for surgery when waiting for the medical response. Thus, we investigated whether biomarkers which could early predict the surgery risk of patients with ASUC on admission.
Study Type
OBSERVATIONAL
Enrollment
146
Colon operation
100% direct approximation of inevitable surgery
Time frame: 30 days
No response to medical treatments
Medical treatments involve glucocorticoids, Immunosuppressant and biologicals for ulcerative colitis. The Oxford Index measured everyday, consisting of CRP and stool frequency, is used to evaluate the response to the treatment. If the Oxford Index does not reduce after 5-day medical treatment, this situation is deemed as no response to medical treatment
Time frame: 5 days
30-day mortality
All-cause mortality within 30 days
Time frame: 30 days
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