Specimen Repository for HIV Immunopathogenesis

N/ACompletedNCT03579381

AIDS Healthcare Foundation9 enrolled

Overview

Specimen Repository for HIV Immunopathogenesis Studies

The goal is to build a large specimen repository for collaborating scientists to run studies of immunity and HIV-1.

Study Type

OBSERVATIONAL

Enrollment

Conditions

HIV-1-infection Acute HIV Infection

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. HIV positive (acutely infected, viremic and elite controllers) 2. Signed Informed Consent Form 3. Age at least 18 years old 4. Immune controllers, two types: "Elite suppressors" (HIV-positive with any three consecutive plasma HIV-1 RNA PCR undetectable while off treatment) or "viremic suppressors" (HIV-positive with any three consecutive HIV-1 RNA PCR \<3000 while off treatment). 5. Acutely infected subjects: Persons identified to have a negative HIV antibody response (ELISA) but positive detection of HIV-1 in the blood (RT-PCR) or individuals who have evidence of a recent (past 30 days) HIV negative result along with a current HIV positive result. Exclusion Criteria: 1. Uncontrolled bleeding diathesis. 2. Pregnant. 3. Inability to provide informed consent.

Locations (1)

AIDS Healthcare Foundation - Public Health Division

Los Angeles, California, United States

Outcomes

Primary Outcomes

HIV progression from acute infection to viral suppression

Outcomes will depend on scientists who use the samples for further study

Time frame: 2 years

HIV progression and control by elite and viremic suppressors

Outcomes will depend on scientists who use the samples for study

Time frame: 2 years

Data from ClinicalTrials.gov

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