Perform a randomized comparison study of dual-antiplatelet (aspirin, prasugrel) and triple-antiplatelet (aspirin, clopidogrel, and cilostazol) preparation using P2Y12 assay in patients with high on-treatment platelet reactivity undergoing stent-assisted coil embolization for an unruptured intracranial aneurysm
Comparison between dual-antiplatelet and triple-platelet preparation
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
198
Aspirin protect tablet
Prasugrel tablet
Clopidogrel 75mg tablet
Seoul National Univeristy Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Incidence of hemorrhagic complications between 2 arms
check minor and major hemorrhagic complications of intra- and post-procedures
Time frame: through study completion (for 3 months)
Change of the level of P2Y12
Check the change of the level of P2Y12 according to each arms during study periods
Time frame: through study completion (for 3 months)
mortality between 2 arms
check mortality after procedures
Time frame: through study completion (for 3 months)
Incidence of thromboembolic complications between 2 arms
check minor and major thromboembolic complications of intra- and post-procedures
Time frame: through study completion (for 3 months)
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Cilostazol tablet