The Effect of Docosahexaenoic Acid Supplementation on Biomarkers of Concussion Over the Course of a Year in Canadian National Rugby Players

Texas Christian University50 enrolled

Overview

Nutrition interventions may present a safe and relatively risk free intervention for protection against subconcussive impacts. Docosahexaenoic acid (DHA, 22:6n-3) is the principal Omega 3 polyunsaturated fatty acid in the brain, playing an integral role in the brain's development and structural integrity. The goal of this study is to determine if supplementation with DHA attenuates blood biomarkers of repetitive head trauma linked to sub-concussive impacts sustained in rugby participation.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Head Trauma

Interventions

Docosahexaenoic Acid (DHA)

Daily administration of docosahexaenoic Acid (DHA). 2 grams of DHA liquid concentrate administered per day throughout trial period.

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Canadian national rugby athletes on 7s and 15s teams Exclusion Criteria: * None

Locations (1)

Texas Christian Universti

Fort Worth, Texas, United States

Outcomes

Primary Outcomes

Blood concentration of neurofilament light protein

Concentrations of neuronally derived proteins measured in blood

Time frame: 12 times throughout course of 1 year

Data from ClinicalTrials.gov

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