Retrospective Study to Estimate the Current Status of Patients With Non-Obstructive coroNary Artery Disease

Merck KGaA, Darmstadt, Germany1,600 enrolled

Overview

The study will estimate the current status of participants with non-obstructive coronary artery disease confirmed via coronary angiography.

Study Type

OBSERVATIONAL

Enrollment

1,600

Conditions

Non-Obstructive Coronary Artery Disease

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants who had typical or atypical angina symptom before Coronary Angiography examination * Underwent CAG between 01 Jan 2013 and 31 Dec 2015 * Other protocol defined inclusion criteria could apply Exclusion Criteria: * Participant with history of percutaneous coronary intervention or coronary artery bypass surgery * Participant with history of myocardial infarction * Participant with history of cardiac transplant or valve surgery * Presenting with Acute myocardial infarction for coronary angiography * CAG showed myocardial bridge and coronary stenosis greater than or equal to 50 percent during systole period * Incomplete or missing data in CAG report * Other protocol defined exclusion criteria could apply

Locations (1)

Please Contact the Merck KGaA Communication Center

Darmstadt, Germany

Outcomes

Primary Outcomes

Percentage of Participants with Non-Obstructive Coronary Artery Disease (CAD)

Time frame: Up to 10 Months

Secondary Outcomes

Percentage of Participants With Combined Cardiovascular Risk Factors

Combined cardiovascular risk factors include: body mass index, smoking habit, hypertension, hyperlipidemia diabetes mellitus, lack of exercise, alcohol intake and family history of early onset cardiovascular disease. Percentage of participants with combined cardiovascular risk factors will be reported.

Time frame: Up to 10 Months

Percentage of Participants With Angina Symptoms

Time frame: Up to 10 months

Percentage of Participants With Pathologic Echocardiography Results

Time frame: Up to 10 Months

Ventricular Wall thickness in Participants With Obstructive and Non-Obstructive Coronary Artery Disease (CAD)

Mean left ventricular posterior wall thickness (LVPW), interventricular septum (IVS) thickness, other ventricular wall thickness will be assessed for the participants with obstructive and non-obstructive CAD.

Time frame: Up to 10 Months

Left Ventricular End-Diastolic Volume (LVEDV) in Participants With Obstructive and Non-Obstructive Coronary Artery Disease (CAD)

Time frame: Up to 10 Months

Left Ventricular End Diastolic Diameter (LVEDD) in Participants With Obstructive and Non-Obstructive Coronary Artery Disease (CAD)

Time frame: Up to 10 Months

Ventricular Wall Motion in Participants With Obstructive and Non-Obstructive Coronary Artery Disease (CAD)

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.