Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge

Cairo University30 enrolled

Overview

Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6 mm). Alveolar socket preservation is thought to deal with this issue as to prevent the loss of alveolar bone dimensions post extraction in the case of delayed implant placement

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Bone Resorption Alveolar Bone Loss Alveolar Bone Resorption Bone Graft Failure

Interventions

Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)PROCEDURE

Filling the socket with Mixing of autogenous bone graft and anorganic bovine bone in a 50:50 ratio

Anorganic Bovine Bone (ABB)PROCEDURE

Filling the socket with Anorganic bovine bone graft material only

Absorbable gelatin spongePROCEDURE

Filling the socket with an absorbable gelatin sponge foam pack

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation. * Both sexes. * No intraoral soft and hard tissue pathology. * No systemic condition that contraindicate implant placement. Exclusion Criteria: * Presence of fenestrations or dehiscence of the residual bony Walls after extraction. * Heavy smokers more than 20 cigarettes per day .(24) * Patients with systemic disease that may affect normal healing. * Psychiatric problems * Disorders to implant are related to a history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site. * Patients that refuse to be called back for implant placement post extraction. * Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration. * Pregnant Females.

Outcomes

Primary Outcomes

Histomorphometrical bone analysis

histological bone core analysis

Time frame: 6 month post primary surgery

Secondary Outcomes

Alveolar Bone marginal loss

CBCT measurements of marginal bone dimensional difference

Time frame: 6 month post primary surgery

Central Contacts

Dina M. Al-Esawy, Masters

CONTACT

01206036365 dr.dina.alesawy@hotmail.com

Dina M. Al-Esawy, Masters

CONTACT

01206036565 dr.dina.alesawy@hotmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.