Characterization of the Autofluorescence of Healthy and Pathological Tissues of Vocal Cords

Centre Hospitalier Universitaire de Besancon30 enrolled

Overview

The aim of this clinical trial is to provide information about autofluorescence of pathological versus healthy vocal folds tissues. Experimentations are performed on vocal folds biopsies obtained from patients, surgered at ENT department, university hospital of Besançon. After being extracted, samples of vocal folds are submitted to excitations at 365 nm, 405 nm and 450 nm; light spectral absorptions are measured, and results are compared to reference anatomopathology.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Laryngeal Neoplasms

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patient view in ENT department, presenting vocal fold lesion that necessitate biopsy * patient informed and with non opposition Exclusion Criteria: * small (\<1mm) and/or brittle sample * Patients in emergency situations, pregnant or nursing mothers, persons deprived of their liberty, minors or protected adults.

Locations (1)

CHRU de Besancon

Besançon, France

Outcomes

Primary Outcomes

hyperspectral fluorescence of vocal folds

Time frame: 30 minutes after biopsy

Data from ClinicalTrials.gov

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