Short Versus Long Interval to Ileostomy Reversal After Ileal Pouch Surgery

Inclusion Criteria: * Signed informed consents. * Man or woman between 18 and 64 years of age. * Ulcerative colitis (UC) or indeterminate colitis (IC) diagnosed by routine clinical, radiographic, endoscopic, and pathological criteria. * Patient will be scheduled for non-emergent proctocolectomy or completion proctectomy with ileal j-pouch anal anastomosis (IPAA) and loop ileostomy (IPAA). * Clinical assessment of patient after IPAA surgery indicates that patient is suitable for early ileostomy reversal Exclusion Criteria: * Age \< 18 or \> 64 years * Colon or rectal cancer * Crohn's disease or suspected Crohn's disease * Prednisone dose \> 20 mg per day (or equivalent other steroid dose) within 4 weeks of scheduled IPAA * Body mass index (BMI) equal to or greater than 40 kg/m2 * Hemodynamic instability (persistent pulse rate \< 50 or \> 120 bpm, systolic blood pressure \< 90 or \> 160 mm Hg, uncontrolled cardiac arrhythmia, or active vasopressor drug use) * Organ transplant recipient (e.g. Liver, Kidney, Pancreas) * Immunosuppression due to chemotherapy drug use or systemic disease. * Sepsis * Renal insufficiency (i.e. serum creatinine ? 2 mg/dl or need for dialysis) * Therapeutic anticoagulation (e.g. venous thromboembolic disease, prosthetic heart valve) * Blood Hemoglobin \< 8 g/dl * Serum Albumin \< 2.5 g/dl * Individualized decision by the surgeon to exclude the patient based on sound surgical judgment * Pregnant patients and female patients who do not satisfy the standard of care requirements of participating centers for an elective surgical procedure. * Clinical assessment of patient after IPAA surgery indicates that patient is not suitable for early ileostomy reversal * Participation in another clinical trial within the last 30 days, or simultaneous participation in another clinical trial * Well-founded doubt about the patient's cooperation.