Ejaculation Preserving Photoselective Vaporization Versus Plasma Kinetic Vaporization Versus Transurethral Resection Of The Prostate: A RCT

Mansoura University84 enrolled

Overview

To Evaluate and compare the outcome and coast of ejaculation sparing management of BPH using 3 different techniques: PVP, PKVP and TURP. Ejaculation sparing TURP group is considered the standard control group. Evaluation will be carried out through a prospective randomized powered trial

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Ejaculation Abnormal BPH With Urinary Obstruction Prostatic Hyperplasia Prostate Disease Prostate Obstruction

Ejaculation Preserving Photoselective VaporizationPROCEDURE

Ejaculation Preserving Photoselective Vaporization

Ejaculation Preserving Plasma Kinetic VaporizationPROCEDURE

Ejaculation Preserving Plasma Kinetic Vaporization

Ejaculation Preserving Transurethral Resection Of The ProstatePROCEDURE

Ejaculation Preserving Transurethral Resection Of The Prostate

Eligibility

Sex: MALEMin age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 1\. Age \>50 years 2. Prostate volume (measured by TRUS): 30-80 gm 3. International prostate symptom score (IPSS )\>15 and quality of life score (QOL)\< 3. 4\. Maximum flow rate of uroflometry \<10 ml/second 5. Patients with active sexual life (or interested) and having the ability to ejaculate and desire to preserve ejaculation. 6\. Failure or intolerance to medical treatment, recurrent urinary infection, urine retention, significant hematuria or deterioration of the upper urinary tract function secondary to BOO. Exclusion Criteria: 1. Bleeding disorders and patients on anticoagulant treatment 2. Histologically proved cancer prostate 3. Neurogenic voiding dysfunction 4. Lower urinary tract malignancy 5. Preoperative ejaculation or sexual dysfunction 6. Presence of stricture urethra 7. Unfit for spinal anathesia -

Outcomes

Primary Outcomes

estimate and compare the ejaculation preservation effect of the 3 techniques (PKVP, PVP and TURP).

assessed by Male Sexual Health Questionnaire (MSHQ)

Time frame: 1 years

Secondary Outcomes

change in flow rate

measured by uroflowmetery in ml/sec

Time frame: 1 years

postoperative complication

measured by Clavien-Dindo Classification scale

Time frame: 1 year

change in patients' symptoms.

measured by International Prostate Symptom Score (I-PSS)