Evaluation of two dressing materials; a Platelet-Rich Fibrin (PRF) dressing and a non-eugenol-based (Coe-Pak™) dressing in the management of free gingival graft and donor site palatal wound.
Evaluation of the usage of platelet-rich fibrin dressing in the management of free gingival graft and donor site palatal wound by evaluation of pain score, healing tissue in both donor and receiving sites, coverage of gingival recession, and the gain of attached gingiva. A total of 20 subjects will be invited to participate in this study from the patients seeking treatment at the Department of Periodontology, Faculty of Dentistry, Damascus University. The study has been approved by the investigator's local Review Board. Subjects will be recruited according to specific inclusion criteria. After completion of medical and dental history questionnaires, patients will sign a consent form after being advised about the nature of the study. Patients will be allocated into two groups (10 patients each). A Platelet-Rich Fibrin (PRF) dressing will be used in both donor and receiving sites in the test group, while a non-eugenol-based (Coe-Pak™) dressing will be used in both donor and receiving sites in the control group . Donor site working time, bleeding (BLE), colour match (CM), pain and re-epithelization (EP) will be evaluated.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
20
A free gingival graft will be used for the treatment of gingival recession
A Platelet-Rich Fibrin dressing (PRF) will be applied in both donor and receiving sites after the free gingival graft.
A non-eugenol-based dressing (Coe-Pak™) will be applied in both donor and receiving sites after the free gingival graft.
Damascus University
Damascus, Syria
The pain score using the visual analogue scale (VAS)
This variable is going to be measured by an visual analogue scale (VAS). The VAS pain scores ranges between 0 to10. (0: no pain, 1: minimal pain, 10: severe pain).
Time frame: The Pain score will be evaluated twice. At T1 (after 2 days of surgery) and T2 (after 7 days of surgery).
Healing index for free gingival graft
The healing index for free gingival graft is an ordinal score: very poor, poor, good, very good and excellent.
Time frame: The healing index will be evaluated twice. At T1 (after one week of surgery) and T2 (after one month of surgery)..
The complete re-epithelialization of the palatal wound
This variable is going to be measured using the peroxide test. Scores are yes or no for showing bubbles.
Time frame: The measurements will be performed at T1 (after 1 week measurement), T2 (after 2 weeks measurement), T3 (after 3 weeks measurement), and T4 (after 4 weeks measurement).
Changes in gingival recession
Miller Class II of Gingival recession is measured from the cemento-enamel junction to the gingival margin of the recessed tissues.
Time frame: The measurement will be performed at T0 (baseline measurement) and at T1 (at three months exactly post-operatively measurement).
Match color of the palatal wound
VAS scores (between 0 and 10. 0: no CM, 10: excellent CM) in comparison with adjacent and contralateral palatal mucosa.
Time frame: The measurement will be performed at T1 (after 1 week measurement) and T2 (after 1 month measurement).
Attached gingival width
Measured from the Mucogingival junction to the gingival Groove.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: The measurement will be performed at T0 (baseline measurement) and at T1 (after 3 months measurement).
Plaque index
Score: none, simple, middle, severe.
Time frame: The measurement will be performed at T0 (baseline measurement) and at T1 (at three months exactly post-operatively measurement).
Gingival Index
Score: none, simple, middle. Severe.
Time frame: The measurement will be performed at T0 (baseline measurement) and at T1 (at three months exactly post-operatively measurement).
Bleeding on probing Index
Score: bleeding, none bleeding.
Time frame: The measurement will be performed at T0 (baseline measurement) and at T1 (at three months exactly post-operatively measurement).
Pocket Probing Depth
Score: normal, simple, middle, severe.
Time frame: The measurement will be performed at T0 (baseline measurement) and at T1 (at three months exactly post-operatively measurement).