Efficacy of Licorice on Reducing Salivary Streptococcus Mutans Versus Chlorohexidine in Caries Risk Patients

Cairo University52 enrolled

Overview

To compare the effect of a natural herbal licorice containing preventive measure alternative to chlorohexidine preventive measure to decrease the effect of streptococcus mutans.

A total number of fifty-two patients will be enrolled in the study. They will be divided into two groups: study group and control group. Study group will be subjected to licorice mouthwash and the control will be subjected to chlorohexidine mouth wash. Salivary bacterial count will be evaluated for both groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Caries, Dental

Interventions

licorice extract mouthwashOTHER

mouth rinse that contains a natural herbal licorice root extract used as a preventive measure that reduce caries index.

chlorohexidine mouthwashOTHER

mouth wash that contains chlorohexidine as an active component

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * over 18 years old * co-operative patients * not allergic to licorice * not allergic to chlorohexidine Exclusion Criteria: * pregnancy * allergic patients to licorice * allergic patients to chlorohexidine * lack of compliance * evidence of parafunctional habits * patients with periodontal disease * xerostomia * participants that receive any microbial agent two weeks prior to the study

Outcomes

Primary Outcomes

salivary bacterial count

streotococcus mutans bacterial count

Time frame: after one week

Central Contacts

nancy helmy, Msc

CONTACT

01002715841 nancy.helmy@dentistry.cu.edu.eg

sherine hafez, Phd

CONTACT

01099296591 sherine.hafez@dentistry.cu.edu.eg

Data from ClinicalTrials.gov

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