Evaluation of PCO2 and PO2 Values in the Pulmonary Artery and Superior Vena Cava

Catholic University of the Sacred Heart50 enrolled

Overview

The study is about comparing blood samples obtained from the superior vena cava and the pulmonary artery. The investigators will compare the values of PCO2 and PO2 from these two sites, in order to see if exists a PCO2 gap and a PO2 gap, different from zero. Moreover the investigators want to find out if these gaps are related with changes in the cardiac output, the hematocrit or if they can predict post operative dysfunctions. Blood samples will be taken at six different times as scheduled by the protocol. Along with the two venous blood samples, an arterial blood sample will be taken too, from a radial of femoral artery catheter.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Heart Diseases

Interventions

blood samplesOTHER

blood samples will be obtained from the superior vena cava (via centra venous catheter), from the pulmonary artery (via Swan Ganz catheter), and from a radial or femoral artery catheter

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * age \> 18 years * patient undergoing cardiac surgery with extracorporeal circulation * hemodynamic monitoring with a central venous catheter and a Swan Ganz catheter placed in the internal left giugulare vein Exclusion Criteria: * severe tricuspid insufficiency * EF \< 50% * SOFA score \>1 in at least one of all the criteria

Locations (2)

catholic University of the sacred Heart

Rome, Italy

Francesca Bevilacqua

Rome, Italy

Outcomes

Primary Outcomes

PCO2 gap changes

See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery

Time frame: two days

PO2 gap changes

See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery

Time frame: two days