Clinical Study of TS-143 in Healthy Adult Male Subjects (Single-Dose Administration)

Inclusion Criteria: 1. Subjects with a body-mass index (BMI) of 18.5 to less than 25.0 at the time of the screening tests 2. Subjects judged by the principal investigator or a subinvestigator to be appropriate for participation in the study based on the results of the screening tests and the tests conducted prior to the investigational drug treatment Exclusion Criteria: 1. Subjects who meet any of the following criteria in the screening tests or the tests conducted on Day -1 and prior to the investigational drug treatment * Red blood cell count: ≥ 535 × 10\^4 /μL * Hemoglobin: ≥ 16.2 g/dL * Hematocrit: ≥ 47.5% * Reticulocyte ratio: Outside of the reference value range 2. Subjects who meet any of the following criteria in the screening tests * Serum EPO concentration: Outside of the reference value range * Ferritin: 30 ng/mL or less, or ≥ 262 ng/mL 3. Subjects who meet any of the following criteria in the vital signs in the screening tests and the tests conducted prior to the investigational drug treatment * Blood pressure: Systolic blood pressure ≥ 140 mmHg, or diastolic blood pressure ≥ 90 mmHg or more * Pulse rate: \< 40 bpm, or ≥ 100 bpm * Body temperature: ≥ 37.5°C