Main objective is to investigate the tolerability of different titration schemes of BI 456906 in otherwise healthy patients with obesity/overweight, and to determine a titration scheme for future studies.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
131
Profil Mainz GmbH & Co. KG
Mainz, Germany
Profil Institut für Stoffwechselforschung GmbH
Neuss, Germany
Cumulative number [N (%)] of patients withdrawn from up-titration by up-titration scheme
Time frame: Up to 132 days
AUC0-168 (area under the concentration-time curve of the analyte in plasma over the time interval from 0 to 168h)
Time frame: Up to 168 hours
Cmax (maximum measured concentration of the analyte in plasma) after first dose
Time frame: Up to 132 days
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