The shortage of organs has always been a problem in pediatric liver transplants due to the lack of donors with an adequate size. Different techniques of hepatic reduction have been described that allow to use larger organs in the pediatric population. However, in these techniques the maximum reduction achieved by segments 2 and 3 is excessive for low-weight children. Since 1997 the liver transplantation group at Hospital Italiano de Buenos Aires has developed and practiced a technique called hepatic hyper-reduction, which consists in reducing the lateral segment of a living donor, adapting the shape and size of the graft to the needs of the recipient. The investigators have performed approximately 50 pediatric liver transplants with live donors in low weight children in whom the hyper-reduction technique has been applied. The aim of the present study is to describe postoperative morbidity and mortality and analyze overall and graft survival.
Study Type
OBSERVATIONAL
Enrollment
58
Live donor liver transplantation using non-anatomical in-situ ultrasound-guided reduction of left lateral segments with preparation of a graft that is larger than a monosegment, but smaller than Segments 2 and 3.
Hospital Italiano de Buenos Aires
Capital Federal, Argentina
Overall survival at 1 year.
Overall survival was defined as the time from surgery to death (all causes) or date of last follow-up, measured in months.
Time frame: Overall survival wil be reported at 1 year after liver transplantation.
Overall survival at 3 years.
Overall survival was defined as the time from surgery to death (all causes) or date of last follow-up, measured in months.
Time frame: Overall survival wil be reported at 3 years after liver transplantation.
Overall survival at 10 years.
Overall survival was defined as the time from surgery to death (all causes) or date of last follow-up, measured in months.
Time frame: Overall survival wil be reported at 10 years after liver transplantation.
Graft survival at 1 year.
Graft survival was defined as the time from surgery to the date of re-transplantation or re-entry to waiting list, measured in months.
Time frame: Graft survival wil be reported at 1 year after liver transplantation.
Graft survival at 3 years.
Graft survival was defined as the time from surgery to the date of re-transplantation or re-entry to waiting list, measured in months.
Time frame: Graft survival wil be reported at 3 years after liver transplantation.
Graft survival at 10 years.
Graft survival was defined as the time from surgery to the date of re-transplantation or re-entry to waiting list, measured in months.
Time frame: Graft survival wil be reported at 10 years after liver transplantation.
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