Despite major advances in the technical aspects of surgical repair of congenital heart diseases, perioperative myocardial damage with low cardiac output remains the most common cause of morbidity and death after repair of congenital heart lesions.
Myocardial sample was obtained from the endocardial surface of the right ventricle and placed in formalin until examination under light microscopy for detection of myocyte cellular edema as a marker of ischemic changes.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SCREENING
Masking
NONE
Enrollment
60
Myocardial cell edema either focal or diffuse was detected in histopathological examination
Myocardial biopsy
Myocardial cell edema either focal or diffuse was detected in histopathological examination
Time frame: within 24 hours
The inotropic score
1 point is assigned for each mcg/kg/min of dopamine and dobutamine, and 10 points is assigned for each 0.1 mcg/kg/min of epinephrine, norepinephrine, and phenylephrine. (i.e. 1 point is assigned for each 10 ng/kg/min of epinephrine, norepinephrine, and phenylephrine.
Time frame: within one month
Serum cardiac troponin level
Samples for troponin I levels at baseline, 6, 12 and 24 hours after aortic cross-clamping.
Time frame: first 24 hours
30-day mortality
number of patients died
Time frame: 30 days
Type of cardiac rhythm on return
Type of cardiac rhythm on return
Time frame: within 24 hours
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