Universal HIV Screening and Targeted HCV Screening in Emergency Department

Centre hospitalier de l'Université de Montréal (CHUM)6,350 enrolled

Overview

Cross-sectional study of patients consulting in the emergency room of the Centre hospitalier de l'Université de Montréal (CHUM), to assess the implementation of an "opt-out" screening program for HIV and HCV and prospective follow-up for 3 months of positive cases.

The purpose of this study is to evaluate the feasibility of routine HIV and HCV screening using an "opt-out" approach at the emergency room of the CHUM and to determine the rate of new positive HIV and HCV cases. A sub-analysis will focus more specifically on HCV in the Quebec equivalent of "baby boomers" (1945-1975) since this is the group that was targeted in the United States. The second phase of this study will evaluate the effectiveness of the linkage to the healthcare system for people diagnosed with HIV or HCV and how fast these people are taken care of and put on treatment.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

6,350

Conditions

Hepatitis C Hiv

Interventions

HIV and HCV screeningDIAGNOSTIC_TEST

HIV test: ARCHITECT HIV Ag/Ab Combo, Abbott HCV test: ARCHITECT Anti-HCV, Abbott

Eligibility

Sex: ALLMin age: 18 YearsMax age: 73 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Individuals attending the emergency room of the Centre hospitalier de l'Université de Montréal Exclusion Criteria: * Individuals unable to opt-out due to their psychological or physical condition

Locations (1)

Centre Hospitalier de l'Université de Montréal

Montreal, Quebec, Canada

Outcomes

Primary Outcomes

Prevalence

Prevalence of HIV and HCV among patients who consult at the ER of the CHUM (overall and undiagnosed cases)

Time frame: 10 months

Secondary Outcomes

Prevalence Among Baby-boomers

Determine the prevalence of new cases of HCV among "baby boomers" (1945 - 1975)

Time frame: 10 months

Opt-out

Determine the percentage of patients that opted-out of the routine screening for HIV and HCV at the ER

Time frame: 10 months

Initial Workup

Among patients with a newly positive HIV or HCV test in the ER, determine the percentage of those who attended a first workup appointment at 1 month

Time frame: 1 month

Cascade of Care

Determine the percentage that completed certain steps of the HIV and HCV care cascades at 3 months, ie confirmation of diagnosis, liver fibrosis assessment (HCV), and treatment initiation (HIV) or prescription (HCV)

Time frame: 3 months

Data from ClinicalTrials.gov

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