Interstitial Lung Disease (ILD). Diagnostic Yield of Surgical Lung Biopsy Versus Cryobiopsy in the Same Surgical Stage.

Inclusion Criteria: * Patients for suspected ILD eligible for lung biopsy reviewed during multidisciplinary approach. * Subject provides informed consent. * A negative pregnancy test in women of child-bearing potential. * Subject is mentally capable of understanding study procedures. * 18 years and older. Exclusion Criteria: * Study subject has any disease or condition that interferes with safe completion of the study including: * Platelet count \< 50,000 or Coagulopathy defined as an International Normalized Ratio (INR) \> 1.5 on the day of procedure, as well as discontinuation of ticagrelor or clopidogrel within 5 days of procedure. * Severely impaired lung function as determined with spirometry evidenced by a forced expiratory volume in 1 second (FEV1) \< 0.8, or radiographically as diffuse bullous disease * Hemodynamic instability with systolic blood pressure \<90 mmHg or heart rate \> 120 beats/min, unless deemed to be stable with these values by the surgical or interventional pulmonary attending physicians * Hypoxemia with pulse oximetry values \<88% or partial pressure of oxygen in arterial blood (PaO2) \< 60 on baseline oxygen requirements * Concurrent participation in another study involving investigational drugs or investigational medical devices * Inability to read and understand the necessary study documents