Prospective Pain Study Comparing Different Treatments After Hand Surgery

Rothman Institute Orthopaedics210 enrolled

Overview

The purpose of the study is to evaluate the efficacy of three different types of pain medication (Oxycodone - an opioid, Ibuprofen - a non-steroidal anti-inflammatory, and Acetaminophen - a non-opioid analgesic) in the management of postoperative pain following single soft tissue procedures of the hand and wrist performed exclusively under local anesthesia without sedation. The results of this study will help define optimal prescribing guidelines following the two most common hand surgeries while also potentially validating the use of opioid alternatives post-operatively in order to help mitigate excessive or unnecessary dispensal of opioid analgesics.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

210

Conditions

Post-operative Pain

Interventions

5mg of Oxycodone every 6 hours as needed for pain

600mg of Ibuprofen every 6 hours as needed for painDRUG

600mg of Ibuprofen every 6 hours as needed for pain

500mg of Acetaminophen every 6 hours as needed for painDRUG

500mg of Acetaminophen every 6 hours as needed for pain

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria 1. Patients indicated to undergo primary, unilateral carpal tunnel release or trigger finger release surgery under local anesthesia alone. 2. Age eligibility is \> 18 years of age. 3. Local anesthesia with 1% lidocaine with 1:100,000 epinephrine and Bicarbonate. Exclusion Criteria 1. Bilateral procedures. 2. Additional soft tissue or boney procedures performed simultaneously. 3. The use of sedation and/or general anesthesia. 4. Pediatric patients (age \< 18 years). 5. Pregnant female patients. 6. Non-English speaking patients. 7. Known allergies or medical contraindications to Oxycodone, Ibuprofen, Acetaminophen. 8. History of chronic pain and/or narcotic use preoperatively.

Locations (1)

Rothman Institute

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Numeric rating Scale for Pain

11-point numeric rating scale (NRS) for pain

Time frame: 2 weeks post-op

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.