The investigators hypothesize that the white matter of patients with obstetric antiphospholipid syndrome deteriorates over time
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
40
1. axial diffusion weighted sequence with 32 gradient encoding directions and two values b, 0 s / mm 2 and 1000 s / mm 2. 2. Fluid-attenuated inversion recovery 3. three-dimensional axial image weighted in T1 4. axial echo-planar image sequence 5. three-dimensional pulse sequence axial flight time
CHU Nimes
Nîmes, France
Mean diffusivity of white matter between groups
mm2/s
Time frame: Day 0
Fractional anisotropy of white matter between groups
Value between 0-1
Time frame: Day 0
Radial diffusivity of white matter between groups
mm2/s
Time frame: Day 0
Mean diffusivity of white matter between controls vs subgroups with only anticardiolipin or Lupus anticoagulant and/or aβ2GP1 antiphospholipid antibodies
mm2/s
Time frame: Day 0
Fractional anisotropy of white matter between controls vs subgroups with only anticardiolipin or Lupus anticoagulant and/or aβ2GP1 antiphospholipid antibodies
Value between 0-1
Time frame: Day 0
Radial diffusivity of white matter between controls vs subgroups with only anticardiolipin or Lupus anticoagulant and/or aβ2GP1 antiphospholipid antibodies
mm2/s
Time frame: Day 0
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