Edwards Cardioband European Post-Market Study, MiBAND

Main Inclusion Criteria: * Age ≥ 18 years; * MR (≥ 2+ by echocardiography); * Patient is eligible to receive the Edwards Cardioband Mitral System Main Exclusion Criteria: * Active bacterial endocarditis * Severe organic lesions with retracted chordae or congenital mal-formations with lack of valvular tissue * Heavily calcified annulus or leaflets * Patients in whom transesophageal echocardiography is contraindicated * Patients who cannot tolerate an anticoagulation/antiplatelet regimen * Patients with known severe reaction to contrast agents that cannot be adequately pre-medicated. * Pre-existing prosthetic heart valve or annuloplasty in the Mitral position * Life expectancy of less than twelve months * Patient is pregnant or lactating