This is a HEV seroprevalence in the health donors in the Canton Ticino study. The pre-donation sampling pouch of each blood donor coming form the Cantone Ticino region will be collected and tested for HEV serology (IgM and IgG).
Pre-donation sampling pouch of fresh and stored frozen plasma collected within the last 5 years will be tested for HEV IgG serology at the National Reference Laboratory of the Blood Transfusion Services SRC in Berne Collected data will be used to determine HEV seroprevalence, actual and in the last 5 years, in the Canton Ticino and to investigate trend and pattern of the HEV infection (seroprevalence by different regional areas, comparison with national HEV data, and correlation with age, sex and place of residence).
Study Type
OBSERVATIONAL
Enrollment
1,447
Collection of one sampling pouch from each blood donor
Swiss Transfusion SRC Canton Ticino
Lugano, Switzerland
HEV blood incidence
HEV incidence assessed through a single periferal blood sample from each donor
Time frame: One year
change in the blood incidence of HEV
Determine the change in the incidence of HEV in the Canton Ticino region in the last 5 years analysing the blood sample of the donors.
Time frame: Five years
Geogarphical distribution of the HEV measured in the blood sample
Determination of the distribution of the HEV infection in different geographical areas of the Canton Ticino analysing donor blood samples
Time frame: Five years
Trend of the HEV infection measured in the blood sample
Evaluation of the trend of the HEV infection in the CantoneTicino compared to other Swiss cantons
Time frame: One year
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