Bemiparin for pregnant women with abnormal umbilical artery Doppler ultrasound
152 women with history of unexplained stillbirths were identified , umbilical arty Doppler ultrasound was conducted for them at 20-22 weeks gestation . they were divided into two group , group one are those with abnormal resistant index (= or more than 0.6) thy received Bemiparin 2500 IU subcutaneously daily up to 24 hours before delivery . Group 2 with normal umbilical artery resistant index received no any interventions just routine antenatal follow up .
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
140
second generation low molecular weight Heparin
multivitamins and routine antenatal follow up
Hawler Medical University
Erbil, Kurdistan Region, Iraq
Stillbirth
Intrauterine fetal death
Time frame: after 20 weeks gestation to the delivery of fetus
Early neonatal death
Death of newborn
Time frame: First week of life
Low birth weight
New borne with birth weight less than 5th percentile in kilogram
Time frame: first hour of life
Preterm labor
delivery of the fetus before 37 weeks gestation
Time frame: 20-37 weeks
Pre-eclampsia
High blood pressure with protein urea
Time frame: 20-41 week gestation
major abruptio placenta
Antepartum hemorrhage
Time frame: 20-41 week gestation
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