The purpose of this study is to explore the perinatal risk factors of preterm birth in China.
Preterm birth is a global scourge, and the leading cause of newborn deaths (babies in the first 4 weeks of life) and raised to the leading cause of death among children under 5 years of age, responsible for approximately 1 million deaths in 2015. In China, the prevalence of preterm increased from 4\~5% in 1990s to 7\~10% in 2010. Preterm birth become a burden to both the family and society. Therefore, the risk factors of preterm birth become the critical issue of both Obstetrics and Neonatology. More importantly, few multicenter prospective studies on risk factors of preterm birth included potential reasons such as maternal occupation, psychology condition and lifestyles during pregnancy were conducted in China. Thus, the aim of our study is to explore the perinatal risk factors of preterm birth nowadays in China.
Study Type
OBSERVATIONAL
Enrollment
6,000
Xiamen Maternal and Child Health Care Hospital
Xiamen, Fujian, China
The Second Affiliated Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
live-born preterm
less than 37weeks gestational age
Time frame: at birth
birth weight (g)
Infant's weight recorded at the time of birth
Time frame: at birth
gestation age (week)
the number of completed weeks of gestation, which was determined by the duration of menorrhoea or confirmed by an early ultrasound scan during pregnancy
Time frame: at birth
Apgar score
determined by evaluating the newborn baby on five simple criteria(Appearance, Pulse, Grimace, Activity, Respiration) on a scale from zero to two, then summing up the five values thus obtained. The resulting Apgar score ranges from zero to 10.
Time frame: 1min after birth
Apgar score
determined by evaluating the newborn baby on five simple criteria(Appearance, Pulse, Grimace, Activity, Respiration) on a scale from zero to two, then summing up the five values thus obtained. The resulting Apgar score ranges from zero to 10.
Time frame: 5min after birth
small for gestational age
a birth weight below the 10th percentile for the gestational age
Time frame: at birth
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