Diabetes in Pregnancy and Pregnancy Outcomes

Tarumanagara University45 enrolled

Overview

To compare the clinical, glycemic profile and therapy as well as pregnancy complications and infant mortality among diabetic mothers in Indonesia.

Pregnancy is a diabetogenic state with increasing burden on the mother's metabolism. Insulin resistance is often found during pregnancy leading to a compensatory increase in pancreatic β-cell response and eventually hyperinsulinemia. Undiagnosed and untreated diabetes in pregnancy have been shown to be linked with numerous comorbidities and complications to both mother and foetus. This study aims to compare the clinical, glycemic profile along with comorbidities, management and outcomes of diabetic mothers. Pregnant mothers with gestational and pregestational diabetes diagnosed under the ICD-10 coding of O24 were included in this study. The inclusion criteria was all patients with primary diagnosis of O24, have visited the clinic at least twice with a complete record of glycemic profile, management and fetal outcomes.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diabetes Mellitus in Pregnancy Diabetes, Gestational

Interventions

Medical Nutrition TherapyDIETARY_SUPPLEMENT

Only given medical nutrition therapy.

InsulinDRUG

Prescribed with rapid acting, intermediate acting, mixed or long acting insulin.

Oral AntidiabeticsDRUG

Prescribed with all types of oral anti-diabetics.

Eligibility

Sex: FEMALEHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical and laboratory diagnosis of Diabetes in Pregnancy (Gestational and Pregestational diabetes) * Mothers must have visited the clinic at least twice throughout their pregnancy, at least one at the first trimester and one at the third trimester Exclusion Criteria: * Pregnancy is still undergoing * Incomplete record of glycemic profile, management and fetal outcomes

Outcomes

Primary Outcomes

Infant Mortality

Infant Mortality either due to abortion, intrauterine fetal death or stillbirth as recorded in medical records

Time frame: Throughout the length of pregnancy, an average of 9 months

Gestational Age at Birth

Infant Gestational at Birth as recorded in medical records