Healthcare-associated infections occur frequently and are associated with patient harm. These infections are becoming more difficult to treat due to antibiotic resistance. It is important that healthcare facilities take the steps necessary to prevent the spread of resistant bacteria between patients.
Two patients undergoing sedation in a randomly selected operating room will be evaluated in a serial manner in order to detect transmission of pathogenic bacteria. Patient care will not change due to their participation in this study; the patients will undergo sedation and surgery according to usual practice. This study involves taking microbiology cultures from various places in the operating room before and after each procedure. Cultures will also be taken from the two patients after they are asleep and from their intravenous tubing. From both patients anesthesiologist, surgeon and their surgical team, cRNA, and nursing staff will also have cultures obtained. Each cultures will be de-identified and given a study ID number before transport to the research laboratory for microbiological assay. The patient's medical record will be reviewed for 30 days after surgery to surveil for documentation of a potential hospital acquired infection.
Study Type
OBSERVATIONAL
Enrollment
83
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Identify transmission dynamics of pathogenic bacteria (i.e. Staph aureus).
Focus on how Staph aureus is transmitted in the operating room by identifying key areas of origin.
Time frame: Intraoperative period
Intraoperative clonal transmission of Staph aureus.
Monitor locations throughout the operating room to document clonal transmission from the area of origin.
Time frame: Intraoperative period
Identify the modes of transmission of pathogenic bacteria ((i.e. Staph aureus).
If transmission of Staph aureus from the site of origin to another site in the operating room arena is documented, identify the modes of transmission.
Time frame: Intraoperative period
Monitor for post operative healthcare associated infections.
Monitor for the presence or absence of healthcare associated infection after undergoing an operative procedure.
Time frame: Up to 30 days following surgery
Surveil for molecular links between pathogenic organisms.
Seek to identify molecular links between causative organisms of infection and bacteria found in the operating room at the time of surgery.
Time frame: Up to 30 days following surgery
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