A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)

Inclusion Criteria: * Healthy males * Age 30 to 65 years of age * Body mass index (BMI) of 18.0 to 35.0 kg/m2 or, if outside the range, considered not clinically significant by the investigator * Must be willing and able to communicate and participate in the whole study * Must have regular bowel movements (ie, average stool production of ≥1 and ≤3 stools per day) * Must provide written informed consent * Must adhere to the contraception requirements Exclusion Criteria: * Subjects who have received any IMP in a clinical research study within the previous 3 months * Subjects who are study site employees, or immediate family members of a study site or sponsor employee * History of any drug or alcohol abuse in the past 2 years * Regular alcohol consumption * Current smoking or use of tobacco products or substitutes. * Current users of e-cigarettes and nicotine replacements products * Radiation exposure * Subjects who have completed 2 ADME studies in the last 12 months * Clinically significant abnormal biochemistry, hematology or urinalysis * Positive drugs of abuse test result * Positive hepatitis B surface antigen (HBsAg), hepatitis C virus antibody (HCV Ab) or human immunodeficiency virus (HIV) results * Evidence of renal impairment at screening * History of clinically significant cardiovascular, renal, hepatic, chronic respiratory or gastrointestinal disease, neurological or psychiatric disorder * Serious adverse reaction or serious hypersensitivity to any drug or the formulation excipients * Presence or history of clinically significant allergy requiring treatment * Donation or loss of greater than 400 mL of blood within the previous 3 months * Subjects who are taking, or have taken, any prescribed or over-the-counter drug * Vaccination with any live vaccine within 4 weeks of study drug administration