Ultrasound-guided Alveolar Recruitment in Laparoscopic Gynecological Surgery

Seoul National University Hospital40 enrolled

Overview

The study aims to compare the degree of atelectasis between ultrasound-guided alveolar recruitment group and conventional alveolar recruitment group in patients receiving laparoscopic gynecologic surgery

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

Conditions

Pulmonary Atelectasis

Interventions

lung ultrasound-guided alveolar recruitmentPROCEDURE

Alveolar recruitment maneuver will be performed under lung ultrasound-guidance. Positive pressure will be not exceed 40cmH2O and duration of positive pressure inflation will not exceed 10 seconds.

conventional alveolar recruitmentPROCEDURE

Alveolar recruitment will be provided with positive pressure of 30cmH2O for 10 seconds

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients scheduled to undergo elective laparoscopic gynecological surgery (laparoscopic ovarian cystectomy or laparoscopic salpingo-oophorectomy or laparoscopic hysterectomy or laparoscopic myomectomy) under general anesthesia, with ASA physical status classification I or II Exclusion Criteria: * Previous history of lung surgery * Patients having pneumonia, pneumothorax, or pleural effusion in preoperative chest X-ray * Patients with COPD, emphysema * Patients with previous history of pneumothorax, or bullae * Morbid cardiac disease * Adolescent aged \< 18 years * Anticipated duration of surgery \< 1 hour

Locations (2)

Jin-Tae Kim

Seoul, South Korea

Seoul National University Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

modified lung ultrasound score at the end of surgery

Both lung ultrasound scores can be calculated by adding up the 12 individual pulmonary quadrant scores yielding a score between 0 (no aeration loss) and 36 (complete aeration loss).

Time frame: At the end of surgery

Secondary Outcomes

modified lung ultrasound score at post-anesthesia care unit (PACU)

Both lung ultrasound scores can be calculated by adding up the 12 individual pulmonary quadrant scores yielding a score between 0 (no aeration loss) and 36 (complete aeration loss).

Time frame: intraoperative

incidence of atelectasis diagnosed by ultrasonography

the presence of atelectasis by ultrasonography

Time frame: intraoperative

arterial blood gas analyses

PaO2, PaCO2, SaO2, O2 index (PaO2/FiO2)

Time frame: intraoperative

incidence of postoperative complications

fever, pneumonia, atelectasis diagnosed by chest X-ray

Time frame: during the postoperative period until discharge from hospital, an average of 3 days

intraoperative mean arterial pressure

mean arterial pressure in mmHg

Time frame: intraoperative

intraoperative SpO2

SpO2 in %

Time frame: intraoperative

intraoperative peak airway pressure

Data from ClinicalTrials.gov

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