Splenectomy During Whole Liver Transplantation

Hospices Civils de Lyon141 enrolled

Overview

Indications for splenectomy during whole liver transplantation remain controversial and splenectomy is often avoided because of common complications. The objective is to evaluate specific complications of these combined procedures.

Data on patients who underwent splenectomy during liver transplantation were retrospectively analyzed . Participants underwent splenectomy as part of routine medical care. Patients undergoing simultaneous liver transplantation and splenectomy were matched to a non-splenectomy group.

Study Type

OBSERVATIONAL

Enrollment

141

Conditions

End Stage Liver Disease

Interventions

SplenectomyPROCEDURE

Splenectomy was performed after hepatectomy, in an extra-hilar manner with manual ligation of splenic vessels.

Eligibility

Sex: ALLMin age: 16 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing liver transplantation between 1994 and 2013 Exclusion Criteria: * Data from living donor patients, split liver transplantation, patients with pre- or post-operative splenectomy in medical history, and patients under 16 years were excluded from analysis

Locations (1)

Hopital de la Croix-Rousse

Lyon, France

Outcomes

Primary Outcomes

3-month post-operative mortality

Time frame: At 3 months post surgery

Secondary Outcomes

Post-operative morbidity

Incidence of portal-vein thrombosis within 3 months post liver transplantation

Time frame: 3 months post surgery

One-year mortality

Time frame: One year after surgery

Mortality at 5 years

Time frame: Five years after surgery

Data from ClinicalTrials.gov

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