To Evaluate the Safety, Tolerability, and Pharmacokinetics Profile in Healthy Chinese Volunteers of TG-2349

Inclusion Criteria: 1. Before starting the study, an informed consent form (ICF) approved by the Institutional Review Board (IRB) is obtained from the subject or his/her legal representative； 2. Male or female, and 18 to 45 years of age inclusive when signing ICF； 3. Body mass index (BMI) in the range of 19.0 to 24.0 kg/m2 and male body weight ≥ 50 kg, female body weight ≥ 45 kg； 4. In generally good physical and mental health status on basis of a medical history review, physical examination and vital signs, 12-lead ECG, and laboratory results at screening； 5. For females, one of the following criteria must be fulfilled 1. Had undergone surgical sterilization, or 2. Subjects of childbearing potential must satisfy the following criteria: Before group assignment, the pregnancy test is negative, and Subjects agree to use an approved contraceptive method (i.e. oral spermicidal agent, condoms, or intrauterine devices) during the entire study period (from signing ICF to the last visit). Subjects must also consent to keep the contraceptive method unchanged until 1 month after the study, and Breastfeeding is prohibited 6. Males must be willing to use a reliable form of contraception (use of a condom or spouses using any of the above standards) during the entire study period (from signing ICF to the last visit)； 7. Have not used tobacco or nicotine-containing products within 1 month prior to the first dose of study drug； 8. Have not drunk alcohol beverages or drank alcoholic beverages less than 12 times within 3 months prior to the first dose of study drug； 9. Willing to abstain from caffeine- or xanthine-containing beverages, including coffee and tea, chocolate, alcohol, grapefruit juice, and Seville oranges juice before 24 hr and during the Stay-on Site period. Exclusion Criteria: 1. Current, prior history, or family history of any disease of sudden cardiac death, myocardial ischemia, myocardial infarction, congestive heart failure, QT prolongation syndrome, hypokalemia, myocarditis, exertional dyspnea, cerebrovascular injury, venous thromboembolism； 2. Requires concomitant medication associated with increased QTc interval (i.e. Class I or III antiarrhythmic agents or with cardiac insufficiency； 3. Any abnormality on 12-lead ECG: PR\>240 ms, PR\<110 ms, QRS\>110 ms, QTc\>450 ms, or bradycardia ( heart rate \< 50 beats/min) at screening or the day -1； 4. Any clinical significant abnormality on 12-lead ECG (i.e. atrioventricular block, TdT, other types of ventricular tachycardia, atrial fibrillation and ventricular flutter, clinical significant abnormality on T wave changes or any abnormality on 12-lead ECG that effects QTc intervals) at screening or the day -1； 5. Systolic pressure\>140 mmHg or \<90 mmHg, diastolic pressure \>90 mmHg, pulse \<50 beats/min or \>100 beats/min at screening or the day -1； 6. Any clinical significant abnormality on chest X-rays or abdominal ultrasound scan at screening； 7. Positive serological test for hepatitis A (IgM anti-HAV), hepatitis B (HbsAg), hepatitis C (anti-HCV antibody), or syphilis at screening； 8. Pregnant or breastfeeding； 9. Any abnormal laboratory values (normal value ±10％) that are considered clinical significant by the Investigator at screening or the day -1； 10. Positive breath alcohol test or urine drug screen at screening or the day -1； 11. Current or prior history of any disease of diabetes, cardiovascular, hepatic or renal impairment； 12. Any malabsorption syndrome or other gastrointestinal disturbances affecting drug absorption； 13. Difficulty with blood collection and/or poor venous access for the purposes of phlebotomy； 14. History of epileptic seizure, mental disorders affecting the subject's compliance with the protocol, suicidal risk, or a history of alcohol or illicit drug abuse； 15. Currently has any disease that seriously affects the immune system, for instance, human immunodeficiency virus (HIV) infection, hematological malignancy, solid cancer or splenectomy； 16. Allergy, hypersensitivity or allergic reaction to Furaprevir or its excipients, or Sulfonamides； 17. History of surgery within 6 months prior to the first dose of study drug； 18. Received any hepatic enzyme inducers or hepatic enzyme inhibitors within 30 days prior to the first dose of study drug through medical history questionnaire (refer to appendix 2)； 19. Received any investigational drugs within 3 months prior to the first dose of study drug； 20. Received any prescription drugs, over-the-counter (OTC) drug, or Chinese herbal medicines within 14 days prior to the first dose of study drug； 21. Received any nutritional supplies, including multivalent cations products (i.e. Ca-, Al-, Mg-, Fe-, and Zn-containing products, sucralfate, antacid, nutritional supplements, multi-vitamin, supplements for metals) within 7 days prior to the first dose of study drug； 22. Blood donation ≥400 ml within 3 months prior to the first dose of study drug； 23. Any disease or situation that would affect the safety of study drug or pharmacokinetics profile by Investigators' judgments； 24. As determined by Investigator, a subject is not suitable to take part in this study.