Sucrose-sweetened Beverage in African-American and Caucasian Women.

Inclusion Criteria: * BMI 25 - 35 kg/m2 Exclusion Criteria: * Does not identify as African-American or non-hispanic White * Glucose intolerance (fasting glucose \>100 mg/dl) * Evidence of liver disorder (AST or ALT \>200% upper limit of normal range) * Evidence of kidney disorder (\>2.0mg/dl creatinine) * Evidence of thyroid disorder (out of normal range) * Systolic blood pressure consistently over 140mmHg or diastolic blood pressure over 90mmHg * Triglycerides \> 150mg/dl * LDL-C \> 130mg/dl * Hemoglobin \< 8.5 g/dL * Pregnant or lactating women * Current, prior (within 12 months), or anticipated use of any hypolipidemic or anti-diabetic agents PROTOCOL TITLE: The Effects of Sucrose Beverage on African-American and Caucasian Women (SAAC) Study Page 4 of 18 Revised: November 27, 2013 * Use of thyroid, anti-hypertensive, anti-depressant, weight loss medications or any other medication which, in the opinion of the investigator, may confound study results * Use of chronic corticosteroids (everyday use for a month or longer) * Use of tobacco * Strenuous exerciser (\>3.5 hours/week at a level more vigorous than walking) * Surgery for weight loss * Diet exclusions: Food allergies, special dietary restrictions, food allergies, routine consumption of less than 3 meals/day, routine ingestion of more than 2 sugar-sweetened beverages or 1 alcoholic beverage/day, unwillingness to consume any food on study menu * Veins that are assessed by the CCRC R.N.s as being unsuitable for long-term infusions and multiple blood draws from a catheter * Any other condition that, in the opinion of the investigators, would put the subject at risk * We will exclude individuals from each of the following special populations: * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers \< 18 years) * Pregnant women * Prisoners