Is Video-assisted Thoracoscopic Lobectomy a Clinical Alternative for Surgically Resectable Pathologic N2 NSCLC Patients

Tang-Du Hospital2,145 enrolled

Overview

The study was designed to compare the safety and effectiveness of vedio-assisted thoracoscopic lobectomy with open lobectomy for patients with surgically resectable pathologic N2 non-small cell lung cancer

The is a multi-center retrospective study. Patients with pathologic N2 NSCLC who underwent VATS or open lobectomy between 2014 and 2017 were included into this study. Clinical data on patient demographic, clinical characteristics, treatment and clinical outcomes will be collected to evaluate the safety and effectiveness of video-assisted thoracoscopic lobectomy for pathologic N2 NSCLC.

Study Type

OBSERVATIONAL

Enrollment

2,145

Conditions

Non-small Cell Lung Cancer

Interventions

VATS lobectomyPROCEDURE

Patients who received lobectomy by video-assisted thoracoscopic surgery

Thoracotomy lobectomyPROCEDURE

Patients who received lobectomy by thoracotomy

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with age \> 18 years old; * Patients with pathologically diagnosed non-small cell lung cancer; * Patients underwent lobectomy by either VATS or thoracotomy between 2014 and 2017; * Patients who received lymphadenectomy for all accessible lymph nodes; * Patients with N2 lymph nodes (+) after surgeries; Exclusion Criteria: * Patients with second primary tumors or multiple primary tumors; * Patients who received chest surgeries before hospitalization; * Patients with superior pulmonary sulcus tumor

Locations (10)

China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

China PLA General Hospital

Beijing, Beijing Municipality, China

Henan Cancer Hospital

Zhengzhou, Henan, China

Outcomes

Primary Outcomes

Overall survival

Time frame: 2014-2018

Secondary Outcomes

Duration of hospital stay [Perioperative outcomes]

Duration of hospital stay \[Perioperative outcomes\]

Time frame: 2014-2017

Postoperative 30 and 90 days [Perioperative outcomes]

Postoperative 30 and 90 days \[Perioperative outcomes\]

Time frame: 2014-2017

Drainage time [Perioperative outcomes]

Drainage time \[Perioperative outcomes\]

Time frame: 2014-2017

Intraoperative blood loss [Perioperative outcomes]

Intraoperative blood loss \[Perioperative outcomes\]

Time frame: 2014-2017

Postoperative complications [Perioperative outcomes]

Postoperative complications \[Perioperative outcomes\]

Time frame: 2014-2017

Data from ClinicalTrials.gov

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