Placenta Development Study

Arkansas Children's Hospital Research Institute15 enrolled

Overview

This study will help us learn more about how the placenta develops.

The primary purpose of this study is to understand the epigenetic signaling events in placental trophoblast development.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Healthy

Eligibility

Sex: FEMALEMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * BMI - 18-25 kg/m2 * at least 18 years of age * singleton pregnancy * less than 36 weeks and plan to deliver in the Little Rock/North Little Rock Area Exclusion Criteria: * Women with pre-existing medical conditions (e.g. diabetes, hypertension, pre-eclampsia, STD, gestational diabetes) * Women who are using recreational drugs, tobacco, or alcohol during their pregnancy. * Women who plan on keeping their placenta following delivery for non-medical reasons.

Locations (1)

Arkansas Children's Nutrition Center

Little Rock, Arkansas, United States

Outcomes

Primary Outcomes

Number of participants that placental syncytial fusion involves epigenetic changes in histone modifications

Number of participants that histone acetyltransferases eszymes, CBP and p300 affect syncytial fusion

Time frame: 40 weeks

Data from ClinicalTrials.gov

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