Predicting Long-term Outcomes After Cardiac Arrest by Using Serum NGAL

Uijeongbu St. Mary Hospital73 enrolled

Overview

This study was performed to determine the prognosis of patients after cardiac arrest using serum markers called NGAL. The initial NGAL values of patients with post-cardiac arrest syndrome are checked by blood tests, and the long-term neurological prognosis and survival rate are collected after 6 months.

Serum NGAL is currently being used as a test to determine the likelihood of developing renal failure. However, in a previous study, serum NGAL correlated with neurological prognosis in post cardiac arrest syndrome patients. This prospective study attempts to see the role of serum NGAL as a prognostic factor by including a sufficient number of patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Out-of-Hospital Cardiac Arrest

Interventions

serum NGALDIAGNOSTIC_TEST

serum NGAL was measured at 0, 24, 48, and 72 hours after recovery of spontaneous circulation.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients who underwent targeted temperature management after out-of-hospital cardiac arrest. Exclusion Criteria: * Patients who did not survived 3 days after cardiac arrest. * Pre-existing end-stage renal disease or dependence on renal replacement therapy

Locations (1)

Uijeongbu St. Mary's Hospital

Uijeongbu-si, Gyeonggi-do, South Korea

Outcomes

Primary Outcomes

Long term neurologic outcome

Patients' CPC score after 6 months (good outcome : CPC score 1, 2 / poor outcome : CPC score 3, 4, 5)

Time frame: 6 months

Secondary Outcomes

Proportion of participants with Overall Survival at 6 months

6-month survival rate of patients'

Time frame: 6 months

Data from ClinicalTrials.gov

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