Laparoscopic Ovarian Cystectomy Versus Aspiration and Coagulation in Ovarian Endometrioma

Shaimaa Mostafa Mohammed Refaay El shemy92 enrolled

Overview

The aim of this study is to evaluate the impact of laparoscopic ovarian cystectomy versus aspiration and coagulation on ovarian reserve and pelvic pain in cases of ovarian endometrioma.

All patients are presenting with ovarian endometrioma. They are all subjected to informed written consent, full history, general examination, local examination and transvaginal ultrasound. Follicular stimulating hormone (FSH), Lutenizing hormone (LH), Anti Mullerian hormone (AMH), Antral follicular count (AFC) and chronic pelvic pain which is assessed by Visual Analogue Scale (VAS) of pain scoring system ,all are to be determined before and after laparoscopic surgery (postoperative three months); for two groups (Group A) cystectomy and (Group B) aspiration and coagulation. Histopathological examination was done to the cystectomy group to confirm endometriosis and detect the presence of healthy ovarian tissue in the excised cyst wall.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

Conditions

Ovarian Endometrioma

Interventions

ovarian cystectomyPROCEDURE

laparoscopic ovarian cystectomy in endometrioma

ovarian cyst aspiration and coagulationPROCEDURE

laparoscopic ovarian cyst aspiration and coagulation in endometrioma

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Female with age group 20-40 years. * Female diagnosed by ultrasound with unilateral ovarian endometrioma ≥3cm. Exclusion Criteria: * Previous ovarian surgery. * Endocrinological diseases affecting ovarian reserve e.g. Diabetes mellitus, hypothyroidism. * Polycystic ovary syndrome (PCO). * Suspicion of ovarian malignancy by ultrasound. * Other pelvic pathology e.g. uterine fibroid, pelvic inflammatory disease (PID). * High basal FSH \>10mIU/mL (milli-international unit per milliliter).

Locations (1)

Cairo University

Giza, Egypt

Outcomes

Primary Outcomes

Exploration of the impact of laparoscopic ovarian cystectomy versus aspiration and coagulation on Anti Mullerian hormone (AMH) as a measurement of ovarian reserve .

Evaluation of ovarian reserve which is measured by Anti Mullerian hormone (AMH) in nano-gram per milliliter (ng/ml) before laparoscopy and after the surgery by 3 months.

Time frame: 3 months after laparoscopy

Secondary Outcomes

Exploration of the impact of laparoscopic ovarian cystectomy versus aspiration and coagulation on Antral Follicular Count (AFC) as a measurement of ovarian reserve.

Evaluation of ovarian reserve by assessment of Antral Follicular Count (AFC) by measuring the number of visible ovarian follicles (2-10 mm mean diameter) that are observed during transvaginal ultrasonography in the early follicular phase (cycle days 2-5) in both ovaries. It is done before laparoscopy and after the surgery by 3 months.

Time frame: 3 months after laparoscopy

Exploration of the impact of laparoscopic ovarian cystectomy versus aspiration and coagulation on chronic pelvic pain.

Pelvic pain is measured by Visual analogue scale of pain (VAS) which is a continuous scale comprised of a horizontal (HVAS) or vertical (VVAS) line, usually 10 centimeters in length, anchored by 2 verbal descriptors, one for each symptom extreme "no pain" (score of 0) and "pain as bad as it could be" or "worst imaginable pain" (score of 10-cm scale). The pelvic pain is assessed before laparoscopy and after laparoscopy by 3 months.

Time frame: 3 months after laparoscopy

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.