A Randomized Clinical Trial of Shenbai Granules in Reducing Recurrence of Colorectal Adenoma

Inclusion Criteria: 1. meet the colorectal adenomatous polyp diagnosis. 2. polypectomy under colonoscopy;Including snare polypectomy,endoscopic mucosal resection,endoscopic submucosal dissection. 3. aged 18-70. 4. sign informed consent. Exclusion Criteria: 1. colonoscopy was reported, but no pathological findings were found. 2. patients with hereditary polyposis. 3. there is reliable evidence that the tumor has infiltrated into the intrinsic mucosal layer,or deep infiltration under the mucosa is suspected. 4. combined with colorectal malignancy or previous history of colorectal malignancy. 5. colonoscopy highly suggests inflammatory bowel disease. 6. pregnant and lactating women. 7. women who recently have a planning pregnant programme. 8. prone to bleeding and using anticoagulants. 9. patients with severe cardiovascular,pulmonary and cerebrovascular diseases and liver and kidney dysfunction (ALT and AST are two times higher than the upper limit of normal value in the laboratory of the center;Serum creatinine and urea nitrogen are 1.5 times higher than the upper limit of the normal value in the laboratory of the center. 10. unstable vital signs. 11. suspect or have a history of alcohol or drug abuse. 12. frequent changes in the working environment or other circumstances are likely to cause loss of interview. 13. drugs (aspirin, folic acid, vitamin D, calcium) with potential to treat colorectal adenomas have been used. 14. those who are participating in other clinical trials.