Efficacy of Magnesium Sulfate on Reducing Renal Colic in the Emergency Department

Henry Ford Health System37 enrolled

Overview

To determine if magnesium sulfate paired with an analgesic medication will improve patient pain from renal colic compared with analgesic alone.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Renal Colic

Interventions

Magnesium SulfateDRUG

D5WDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age \>18 years old and \<100 years old. * Patients seen in the Emergency Department at Henry Ford Macomb hospital. * Patients that are A+Ox3. * Patients who have typical presentation for renal colic. Exclusion Criteria: * Age \<18 years. * Patients with a history of dementia, acute delirium or altered mental status. * Patients with inability to consent to study or inability to fill questionnaire independently. * Patients with chronic kidney disease and allergies to study drugs. * Patients that are pregnant (women who are of child-bearing potential will be screened with a urine BHCG). * Patients with stroke activation or symptoms. * Patients with trauma activations. * Patients over the age of 100 years old are excluded as they make up a small percentage of the population and may become identifiable because of their age. * Imaging study does not show evidence of ureteral stone.

Outcomes

Primary Outcomes

Pain Score Change

We asked the patient's pain score on a scale of 0-10 with 10 being the highest amount of pain and 0 no pain, before and after treatment (approximately 1 hour). Primary Outcome was the change in score before and after treatment.

Time frame: 1 hour after the completion of treatment medication (Placebo or Study Drug)

Secondary Outcomes

Percentage of Participants Requiring Opiates for Additional Pain Control

We analyzed how many patients required additional pain control with opiates between the two treatment groups.

Time frame: Any opiate administration required after re-evaluation of pain score after initial treatment with either placebo or study drug

Data from ClinicalTrials.gov

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