Probe-based confocal laser endomicroscopy (pCLE) has been shown to a reliable diagnostic method enabling in vivo microscopic imaging during ongoing endoscopy. Usually fluorescein then serves as a contrast agent for pCLE, but it does not allow direct nuclear visualization, must be injected, leads to a transient skin discoloration, and may have allergic side effects. This study aimed to establish a single topical dye, cresyl violet (CV) for pCLE imaging, to describe pCLE interpretation criteria for the characterization of colorectal polyps with histopathological correlation, and to perform the validation of these criteria.
Study Type
OBSERVATIONAL
Enrollment
60
Department of Gastroenterology, Qilu Hospital, Shandong University
Jinan, Shandong, China
The pCLE with topical CV interpretation criteria for the characterization of colorectal polyps with histopathological correlation
Time frame: 5 months
Number of diagnostic agreement between pCLE with topical CV and histopathological results
Time frame: 5 months
Number of participants with procedure-related adverse events
Time frame: 5 months
Number of pCLE imaging failure with topical CV
Time frame: 5 months
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