Vertebral compression fractures in osteoporotic patients is a major healthcare problem. Percutaneous vertebroplasty is commonly used to restore stability of the vertebra and to alleviate pain. However, the anesthetic techniques commonly used during these procedures such general anesthesia or a combination of local anesthesia and sedation are not satisfying as they are associated either with side effects or insufficient pain reduction. This study compares the standard procedure of local anesthesia to a new technique of fluoroscopy-guided epidural anesthesia carried out by the radiologist. The investigator's hypothesis is that fluoroscopy-guided epidural anesthesia * provides better pain relief during the injection of high viscosity cement * and thus, reduces the need of additional intravenous analgesia by remifentanil (morphine analogue) * minimizes remifentanil potential adverse effects such as respiratory depression, hypoxemia, pruritus and nausea * improves working conditions and satisfaction of the radiologist * improves the global satisfaction of the patient It is a monocentric, prospective, comparative and randomized study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
100
intravenous analgesia by remifentanil is provided and adapted to the patients' needs during the whole procedure
Identification of the epidural space using fluoroscopy and the injection of a small quantity of contrast medium or air. An additional, anesthesia combined with intravenous analgesia by remifentanil is provided and adapted to the patients needs during the whole procedure
Hôpitaux Universitaires de Strasbourg
Strasbourg, France
RECRUITINGMorphine used in the procedure
Maximal target dose of remifentanil used during the procedure to obtain a satisfactory pain reduction during cement injection
Time frame: 1 day
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